Aperture
REGNToplinePhase 3Window

Phase 3 topline — Ravulizumab

Regeneron Pharmaceuticals, Inc. · NASDAQ · $70.5B market cap

Bias Score

P(positive outcome)

Forecast move

Date confidence

45%

Company guidance for a period, e.g. 2H 2026.

What this event is

A Study to Evaluate How Safe Pozelimab + Cemdisiran Combination Therapy is and How Well it Works in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria (PNH) Who Have Not Recently Received or Have Not Received Complement Inhibitor Treatment

Drug
Ravulizumab
Mechanism
—
Indication
Paroxysmal Nocturnal Hemoglobinuria
Primary endpoint
Percent change in lactate dehydrogenase (LDH)
Enrollment
202
Source
ClinicalTrials.gov

Full dossier

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Trial design and what the registration does and does not record, the primary endpoint and how it is assessed, where the date comes from and how firm it is, and the balance-sheet position going into the print.

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How the model got here

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Feature attribution

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Two-sided forecast

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Company

Market cap
$70.5B
Cash
$8.0B
Runway
—
Approved products
0

Research, not advice. Aperture is not a registered investment adviser or broker-dealer and does not provide personalised recommendations. Nothing here is sized to your circumstances. Trial details come from the sponsor's own ClinicalTrials.gov registration, which sponsors revise; the date is the registered primary completion date, not a commitment.